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- Herausgeber: Youcanprint
- Kategorie: Ratgeber
- Sprache: Englisch
- Veröffentlichungsjahr: 2021
You Are About To Learn The Ins And Outs Of Cancer, Including How To Starve Cancer Cells Naturally Using Different Techniques To Enhance The Effectiveness Of Therapy! Cancer is one of the leading causes of death in the world, accounting for about 10 million deaths, yet, according to the World Health Organization, many of these deaths can be avoided. If you've been affected directly or indirectly by this condition, having enough of the right information can save your life and that of anyone close to you, who might or might not have been diagnosed with it yet. But I imagine this is not the first place you've come looking for answers, in which case, you must have been wondering: What is the true nature of cancer? How does cancer grow? Is there a way to defeat the condition naturally? Can I survive and go back to normal if I am diagnosed with cancer? If I am right, then you're at the right place, which I'm proud to say will be the last place you'll ever visit to get answers. This book is here to give you a clear insight into one of the most frustrating conditions on the planet. It goes into the details of the nature of cancer, how cancer grows and how scientists starve the cancer cells to stop their proliferation and harm in the human body, as well as what you need to do to improve your body's fighting ability and reduce the risk of these harmful cells and so many other details that you need to know to understand this condition inside out. More precisely, the book will teach you: The basics of cancer, including what it really is, how it develops, the different types of cancer and more What cancer cells need to grow and how to use your understanding of the nature of cancer cells to starve them The risks that come with cancer How to eat to defeat cancer today and everyday How the immune system works How cancer starvation therapy works The VDAs-based cancer starvation therapy How to use glutamine to starve cancer cells …And so much more! So if you've been on a search for a comprehensive, insightful and detailed beginners' guide to cancer, which is not only simple but interesting and motivating to read, then herein lies what you've been looking for. In a minute, you'll be armed with all the information you require to confidently know what is being done about cancer in the hidden cancer research and treatment facilities, and the part you have to play to handle and prevent it to save your life, or that of someone close to you. You don't have to waste another second, Click Buy Now With 1-Click or Buy Now to get started!
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HOW TO STARVE CANCER
Complete Guide about Cancer's
History, Treatment, and Prevention
Kelly Leary
Copyright by Kelly Leary All rights reserved.
This eBook is provided with the sole purpose of providing relevant information on a specific topic for which every reasonable effort has been made to ensure that it is both accurate and reasonable. Nevertheless, by purchasing this eBook, you consent to the fact that the author, as well as the publisher, are in no way experts on the topics contained herein, regardless of any claims as such that may be made within. As such, any suggestions or recommendations that are made within are done so purely for entertainment value. It is recommended that you always consult a professional prior to undertaking any of the advice or techniques discussed within.
This is a legally binding declaration that is considered both valid and fair by both the Committee of Publishers Association and the American Bar Association and should be considered as legally binding within the United States.
The reproduction, transmission, and duplication of any of the content found herein, including any specific or extended information, will be done as an illegal act regardless of the end form the information ultimately takes. This includes copied
versions of the work, both physical, digital, and audio unless express consent of the Publisher is provided beforehand. Any additional rights reserved.
Furthermore, the information that can be found within the pages described forthwith shall be considered both accurate and truthful when it comes to the recounting of facts. As such, any use, correct or incorrect, of the provided information will render the Publisher free of responsibility as to the actions taken outside of their direct purview. Regardless, there are zero scenarios where the original author or the Publisher can be deemed liable in any fashion for any damages or hardships that may result from any of the information discussed herein.
Additionally, the information in the following pages is intended only for informational purposes and should thus be thought of as universal. As befitting its nature, it is presented without assurance regarding its prolonged validity or interim quality.
Trademarks that are mentioned are done without written consent and can in no way be considered an endorsement from the trademark holder.
Introductions
For decades, scientists have been trying to stop cancer by blocking nutrients from reaching tumor cells, effectively robbing
tumor cells from the food required to expand and proliferate.
These attempts have also been frustrated that cancer cells are nimble, depending on multiple contingency routes to continue to expand.
Researchers have manipulated a specific weak point in the metabolism of cancer cells, causing tumor cells to expose backup fuel supply routes on which they rely when this vulnerability is disrupted. Mapping these secondary pathways, researchers have also established drugs that block them. A major clinical study of cancer patients is currently being prepared to test this therapeutic approach.
Like a healthy cell, a sarcoma cell depends on external supplies of arginine, an essential building block of proteins. Remove environmental arginine and the cell must initiate a cycle called autophagy, or "self-eating," to live. A second attack on the survival mechanism, then destroys the cells Studying human cancer cells and the mice injected with patient tumor samples, the researchers prove that a double strike — the elimination of the weak point and one of the tumor cells 'replacement pathways — is effective against several hard-to-treat cancers.
While found in several forms of cancer, the weak point is especially prominent in sarcomas — rare skin, muscle, bone, cartilage, and connective tissue cancers, doctors treat sarcomas mainly with conventional surgery, radiation and chemotherapy, although these therapies are sometimes not successful.
It is known that this metabolic deficiency is found in 90% of sarcomas Healthy cells may not have this flaw. We have been attempting to establish a treatment that takes advantage of the metabolic deficiency so, ideally, it can only treat the tumor.
Essentially, the mutation helps one to compel the tumor cells to die. "In order to expand and proliferate, the tumor cells must
have simple building materials. The work approach is focused on the assumption that the overwhelming majority of sarcomas have missed the capacity to produce their own arginine, a protein building block that cells use to create more of themselves. In the absence of this capacity, the cells will extract arginine from the external area. The stock of arginine in the blood is sufficient, and the cancer cells have little trouble scavenging it. But removing the environmental supply of arginine and cells is a issue.
"If we use a medication to deplete arginine in the blood, the cancer cells fear as they have depleted their fuel source," Van Tine said. "Now they're rewiring to continue and live. For this research, we used this rewiring to classify medications that block secondary pathways. "Like other cancer treatments, the loss of arginine in the blood does not impact healthy cells. Healthy cells do not depend on foreign sources of arginine since they may not have a metabolic deficiency in the cancer. We tend to produce their own arginine, but there is no mediated malnutrition in regular cells even though there is no arginine in the blood. This technique is focused on the tumor's properties — specifically, it shuts down tumor metabolism and nothing else.
Unable to produce or receive external arginine, the fuel supply routes of the tumor cells are pushed inward. Cells may continue to metabolize their internal supply of arginine in a cycle called autophagy or self-eating. In the case of sarcomas, it delays or delays down the development of cancer but does not destroy the
cell. Throughout this phase, tumor cells seem to be buying time to rediscover another internal work-around.
"Cancer doesn't disappear because you interrupt the primary fuel source," Van Tine said. "Because of this, it transforms all these roads to redemption. Within this article, we established the mechanisms of salvage. And we found that when you poison them, you destroy the cells, too. Our research has shown that tumors are gradually diminishing in these conditions. It is the first time that tumors have been shown to reduce utilizing only metabolic medications with no other anti-cancer approaches.
The arginine-depleting medication is now in clinical studies evaluating its protection with efficacy against kidney, lung, pancreatic, breast and other cancers. But, to date, it has been unlikely to succeed as it has triggered the regeneration mechanisms that enable cancer growth to begin. Researchers also proposed that the medication can still be a critical mitochondrial treatment for cancer as long as it is used in conjunction with other medications targeting replacement pathways.
If cancer cells with this metabolic deficiency are depleted of environmental arginine, they are required to switch from a glucose-burning mechanism to a mechanism that consumes another fuel called glutamine. Researchers also demonstrated that the application of a glutamine receptor to the arginine-depleting product is toxic to the cells. Eliminating arginine from the blood often re-wires serine biology, another backup power, and incorporating serine inhibitors often triggers cell death.
This technique may be extended outside uncommon sarcoma tumors, since the metabolic disorder is also found in many cancers, including other forms of breast, colon, lung, brain, and bone tumors, the researchers said. The latest research provides
evidence demonstrating specific anti-tumor responses in cell lines of both forms of cancer.
Both medications used in the research are now currently licensed by the U.S. Health and Medication Treatment for various diseases or in current clinical studies on cancer medications.
Calorie restriction (CR) reduces malnutrition and has anticancer activity in multiple preclinical models. CR is gradually being extended to human cancer as a sensitizing technique before chemotherapy regimens. Although the beneficial effects of CR
are generally recognized, the processes by which CR influences tumor growth are not well known. In several cell types, CR and other nutritional stress may cause autophagy, which offers energy and metabolic substrates that are vital to survival. We believed that reducing the supply of extracellular and intracellular substrate by combining CR with autophagy inhibition would suppress tumor growth more efficiently than either drug alone.
Results: The 30 per cent CR diet opposed to control diet in nude mice resulted in substantial reductions in body weight, blood glucose, cortisol, cortisol-like growth factor 1 and leptin rates at the same period as elevated adiponectin rates. Metabolic analyzes of CR-fed, compared to control-fed, nude mice revealed substantial reductions in circulating glucose and amino acids and large rises in ketones, suggesting a change to fat metabolism.
In a nude mouse xenograft model involving H-RasG12V-transformed immortal kid mouse renal epithelial cells with (Atg5+/+) and without (Atg5-/-) autophagic ability, the CR diet significantly reduced tumor development. Tumor formation and growth was highest for Atg5+/+ tumors in control-fed mice,
moderate for both Atg5+/+ tumors in CR-fed mice and Atg5-/-
tumours in control-fed mice, and lowest for Atg5-/-tumours in CR mice. In Atg5+/+ tumors, autophagic flux was increased in CR-fed relative to control-fed mice, indicating that the pro-survival effects of autophagic induction that counteract the tumor suppression effects of CR. Conclusions: Combined restriction of extracellular (via CR) and intracellular (via autophagy inhibition) energy sources and nutrients inhibits Ras-driven tumor development more efficiently than either CR or autophagy deficiency alone. Interventions addressing both systemic energy balance and tumor-cell intestinal autophagy can reflect a new anticancer strategy.
Chapter One
What Is Cancer
Cancer is the term assigned to the group of diseases connected to it. In both forms of cancer, certain cells of the body tend to
differentiate without stopping and spread to neighboring tissues.
Cancer may begin virtually anywhere in the human body, which is made up of billions of cells. Normally, human cells expand and split in order to create new cells when the body requires them. As cells grow old or become injured, they die, and new cells take their place.
Nonetheless, this organized mechanism breaks down as cancer arises. When cells are more and more dysfunctional, old or weakened cells live until they die, and new cells develop when they are not required. Such extra cells may grow without stopping and can develop tumors called tumors.
Most cancers develop solid tumors, which are tissue masses.
Blood cancers, such as leukemia, usually do not develop solid tumors.
Cancer tumors are malignant, which means they can grow to or enter surrounding tissues. In fact, as such tumors develop, certain cancer cells can break down and migrate to distant parts of the body via the blood or lymph system, creating new tumors far from the original tumor.
Unlike malignant tumors, benign cancers may not grow to or attack surrounding tissues. Nevertheless, benign tumors can often be very big. Normally, they do not grow again after extracted, though malignant tumors often do. Like other benign
cancers in many areas of the body, benign brain tumors may be life threatening.
Differences between Cancer Cells and Normal Cells Cancer cells vary in several respects from regular cells that cause them to develop out of control and become invasive. An essential distinction is that cancer cells are less advanced than regular cells. This is, although regular cells develop into very distinct cell forms with different roles, cancer cells do not. It is one explanation that, unlike regular cells, cancer cells tend to grow without halting.
In fact, cancer cells are able to disregard signs that usually warn cells to avoid dividing or start a cycle known as programmed cell death, or apoptosis that the body uses to get rid of unneeded cells.
Cancer cells may affect normal cells, proteins, and blood vessels that surround and support the tumor — an region known as the microenvironment. For example, cancer cells may stimulate neighboring normal cells to create blood vessels that provide oxygen and nutrients to tumors that they need to expand. Such blood vessels also absorb tumor waste materials.
Cancer cells are most frequently able to escape the immune system, the network of muscles, tissues, and specialist cells that defend the body against diseases and other disorders. While the immune system usually destroys weakened or dysfunctional cells from the body, certain cancer cells are able to escape from the immune system.
Tumors can also use the immune system to remain alive and develop. Of example, with the aid of some immune system cells that usually inhibit a uncontrolled immune reaction, cancer cells may potentially block the immune system from destroying
cancer cells.
