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An appetite-suppressing prick once a week disproves the conventional belief: eat less, move more, in other words, abstinence and discipline. In fact, obesity is due to biology, not lack of willpower. Medical research into drugs to combat diabetes has achieved a fantastic side effect: Weight losses of 15 percent or more! Tiny amounts of imitations of so-called incretins act for 168 hours. The body's own incretins only manage this for two minutes. Hope, hype or humbug? Social media spurs discussion. Serious need for clarification. Yes, semaglutide and tirzepatide are the substances of the hour. But some other diabetes pricks are counterproductive and increase weight.SÖDGMis r,u,tryt htstzk gxgkmz gkg x,gxölrrgäGNÄS
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Seitenzahl: 92
Veröffentlichungsjahr: 2023
Pricking slim with Ozempic like Elon Musk
Anti-fat injections Ozempic,
Wegovy and Mounjaro in practice test
Imprint
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Disclaimer
The following publication is for informational and educational purposes only. It is not intended as a substitute for medical advice or medical treatment. A medical expert should be consulted before taking any health action. The combined use of dietary supplement or herbal substances and prescribed medications without the consent of your health care professional is not recommended. The authors, publisher, distributor, and all those named in this publication assume no liability or responsibility for any loss or damage incurred or alleged to have been incurred as a result of the information conveyed in this publication.
IGK Verlag
22393 Hamburg
Volksdorfer Weg 81c
Germany
Authors: Dr. med. Jan-Dirk Fauteck, Imre Kusztrich
Copyright © IGK Verlag 2023
ISBN: 9783987564284
Photos: © Engel-Fotolia.com, © Abundzu - Adobe Stock.
Foreword
1.3 billion clicks because of a small prick
A question of life expectancy
Abdominal hormones play fate
The brain notices every bite
Insulin resistance perpetuates obesity
Now the ingenuity of the human metabolism takes revenge
Two substances decide about diabetes
Diabetes drug with fantastic side effect
First seven, then one prick a week
Weight loss miracle without headlines
Carbohydrates and heart risks
The first study with an even higher dose
This is how the pen is used
In a nutshell
TikTok, MD
Ideal for your favorite pastime in Hollywood
Ozempic face, Ozempic body
Elon Musk also animated men
Main difference: weekly injections
Less fat and also less muscles
A product of two decades of research
Serious questions come with semaglutide
Do you really need to inject for a lifetime?
Only bariatric operations are more effective
The upcoming injections can do even more
Weight, fat, muscle and bone - what's really happening, after all?
Comment: "Why weight loss drugs are not the answer to obesity"
Once again, Twitter, TikTok and celebrity confessions on Facebook have helped drugs achieve sudden global fame. However, the hype surrounding powerful fat loss through slimming injections with the active ingredients semaglutide and tirzepatide belies any hype surrounding the more than 30 Hollywood diets to date since the "Grapefruit Diet" in the 1930s.
On social media, the drugs Ozempic and Wegovy generate several million views day after day. Their substance is injected into the subcutaneous fat of the abdomen by means of a pen. Their ingredient was intended to treat diabetes. Their benefit regarding extreme weight loss was discovered by accident.
Experts see this as just the beginning.
Injections with the drug tirzepatide, which was originally approved for diabetes, have just passed Phase 3 for use also for weight loss at the U.S. Food and Drug Administration, F.D.A. This is maturing into a super shot with extra benefit, because it will also be associated with improved health. It achieves weight loss while controlling blood sugar. This can save serious secondary diseases. This dual-function pen with the brand name Mounjaro could also be launched on the market as an official anti-fat injection before the end of 2023 and become the world's best-selling drug of all time.
Extreme overweight and obesity are currently considered the number one unresolved health risks. That is why pricks to the subcutaneous fat are experiencing strong official support.
However, the new situation touches on numerous aspects of ethics. For example: Will only the wealthy be able to opt for weekly injections because health insurance companies will not cover the high costs?
On the positive side: These drugs mimic the body's own hormones, as if they were released into the bloodstream by glands with internal secretions.
On the negative side: While the public hails the main effect of guaranteed severe weight loss, manufacturers point to side effects primarily in the gastrointestinal tract because perhaps nausea, vomiting and loss of appetite seem less of a concern. More serious other risks fall under the radar.
There is still a lack of findings on the long-term effects of the injected substances. Scientific studies with other weight loss drugs, after disappointing results, demonstrate extremely rare risks such as suicidal thoughts, of which the general public has no idea. There is even talk of cancer in connection with extremely high doses in animal studies.
In social media, however, according to a report in the lifestyle magazine "Vogue," quite different concerns are now being discussed. For example, the Ozempic face phenomenon. The rapid loss of fat namely also affects the face and changes it so that it may become wrinkled.
So in all fairness, a lot needs to be said about slimming ...
Snapshot.
A question on Twitter on Oct. 1, 2022, to the social media platform's new owner Elon Musk and his two answers may have been the turning point.
An attractive dark-haired real estate agent named Eva McMillan in Brevard County, Florida, with a luxurious beachfront, owner of the first Tesla Model S Plaid in the Sunshine State with all-wheel drive, three motors in carbon pods and over 1,000 horsepower, tweeted to the go-getting businessman, "Hey, @elonmusk, what's your secret? You look awesome, fit, ripped and healthy. Lifting weights? Eating healthy?"
—Eva McMillan ♥️ (@EvasTeslaSPlaid) October 1, 2022
Elon Musk, son of a Canadian nutritionist, immediately responded with, "Fasting." On Oct. 2, he added, "And Ozempic/Wegovy."
—Elon Musk (@elonmusk) October 2, 2022
However, the members of the approval committee for Wegovy did not have people like Elon Musk in mind as beneficiaries of this anti-fat injection. At a height of 188 centimeters, his body weight might have fluctuated between 82 and 90 kilograms over the past twelve months. The medical indication for injections for targeted weight loss, on the other hand, is quite different: obese body mass index from 30, or for people with B.M.I. from 27 and with a metabolic disease such as diabetes or high blood lipids.
The F.D.A. guidelines also stipulate that the use of the active ingredient semaglutide be flanked by a calorie-reduced diet - facilitated by the drug - and increased physical activity.
There was no longer any question of such medical self-evidence after Elon Musk's highly publicized praise. Those who follow the highly regarded entrepreneur in particular must allow themselves to be asked the question: Why not intermittent fasting? After all, he gave two important tips: Fasting and Wegovy, to which he added Ozempic a few days later. However, those who use the drug semaglutide without adapted consideration of food, use it differently than it has been tested in studies. This could mean that some side effects are more likely to occur. Six months later, his first two taciturn answers alone had already been viewed more than 37,100,000 times.
The then only second richest man in the world after the crash of the stock exchange price of the Tesla share followed up. The media speculated that he had even lost up to 30 kilos. Elon Musk again played along, repeating, "Fasting, Ozempic/Wegovy and no delicious food near me."
The drug names Ozempic, Wegovy, Mounjaro, and their active ingredients semaglutide and tirzepatide reached more than 1.3 billion clicks by the end of May 2023.
Nearly three-quarters of the American adult population is severely overweight or obese, according to the Centers for Disease Control and Prevention. Both situations are classified as separate diseases by the World Health Organization.
Obesity in particular, medically referred to as obesity, is a risk factor for diabetes, cardiovascular disease, various cancers, muscle disease and joint disease. These threats are associated with a higher likelihood of dying prematurely.
Anti-aging medicine has a much more extensive list and also includes dementia and stroke, which occur primarily in old age, as long-term consequences of such metabolic disorders.
It is a worldwide problem that is increasing. Since 1975, the proportion of people with obesity has tripled. The countries united in the international Organization for Economic Cooperation and Development, OECD, already spend 8.4 percent of health care expenditures on obesity-related treatments.
In Germany, too, the figures have been rising steadily since 1990, or so it is estimated. On Feb. 18, 2020, the University of Goettingen put the annual cost of overweight and obesity in Germany at 29.39 billion euros in 2017. 102,000 people died prematurely from diet-related diseases, which was 9.4 percent of the total 954,874 deaths.
Source: "Nutrition Policy and Individual Struggle to Eat Healthily: The Question of Public Support." Department of Agricultural Economics and Rural Development, Marketing of Food and Agricultural Products, University of Goettingen, Göttingen, Germany. February 18, 2020).
The most recent figures for Germany are from the Robert Koch Institute, Berlin, September 14, 2022. 46.6 percent of women and 60.5 percent of men in our country are severely overweight or obese. Nearly 13 million adults in Germany suffer from obesity. Up to midlife, more of them are men, after which women catch up.
The first aspect to be highlighted always is the diet-disease relationship. In this sense, metabolic alterations such as diabetes mellitus (DM) and obesity, among others, have in recent years become the most prevalent non-communicable diseases, which in turn provokes a high health-associated cost. For that, there is increasing interest in finding preventive and therapeutic solutions.
Numerous studies demonstrate the broad benefits of increased physical activity in terms of generally better fitness, a strengthened cardiovascular system, and better mental health.
The widely held view that too many pounds are primarily a result of a lack of willpower, discipline, and poor choices began to soften.
The American Medical Association declared severe obesity a chronic disease back in 2013. Some immediately complained at the time that devaluing the importance of discipline, conscious eating and exercise made it easier for sufferers to escape responsibility. Others saw the disease label as a spur to additional medical research, coordination of promising approaches, and increased searches for ways to lose weight.
Two definitions are now widely accepted.
Disease is a condition that impedes normal functioning and manifests with typical symptoms.
Extreme obesity is a chronic, repetitive disease with specific behavioral patterns during which fat mass is promoted that disrupts or interrupts functions. This leads to negative consequences for the metabolism, that is, for the processing of food with biological-mechanical and mental health consequences.
"Whatever the problem - walking alone will reduce it" ... this is a popular approach among health experts. Walking 7,000 to 10,000 steps daily appears to reduce the likelihood of earlier death. Weight lifting once or twice a week can also prolong life, except for death from cancer.
Once it comes to severe obesity, however, lifestyle improvements alone won't help.